Indlela yokusebenza ye-Thiamethoxam ifinyelelwa ngokuphazamisa isimiso sezinzwa sesinambuzane esiqondiwe lapho isinambuzane sidla noma simunca ushevu emzimbeni waso.Isinambuzane esiveziwe silahlekelwa ukulawula umzimba waso futhi sibe nezimpawu ezinjengokudikiza nokudlikizela, ukukhubazeka, nokufa ekugcineni.I-Thiamethoxam ilawula ngempumelelo izinambuzane ezincela nezihlafunayo ezifana nama-aphid, i-whitefly, thrips, ricehoppers, ricebugs, mealybugs, ama-white grubs, amabhungane amazambane, ama-flea beetle, ama-wireworms, amabhungane aphansi, abavukuzi bamaqabunga, nezinye izinhlobo ze-lepidopterous.